Oenothera biennis

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Latest Edit: Hector 2014-03-18 (EDT)

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Evening-primrose6173.jpg

Evening Primrose (Oenothera biennis) is used to treat a range of conditions including digestive, immune and women's health concerns. To explore the characteristics, medicinal uses and prescribing considerations of this herb in more detail, check out the references indicated.[1], [2]

Characteristics

  • Common Names: Evening primrose, King's cure all, Tree primrose, Sundrop
  • Family: Onagraceae
  • Habitat: Oenothera biennis is native to North America and is now found in many temperate climates. It thrives in open areas, especially dunes and sandy soil.
  • Parts Used: Leaves, stem, bark, flowers, see (Evening primrose oil or EPO)
  • Constituents: Fixed oil containing gamma-linolenic acid (GLA) and linoleic acid
  • Medicinal Actions:
Herb: astringent, sedative, phytoestrogen
Oil:Hypotensive (via GLA, a prostaglandin E1 precursor), see Cardiac Tonic. Decreases PMS (tension and bloating), anti-inflammatory, nutritive, antiallergic,

Uses

Historical Uses:

Oenothera biennis was historically used by North American Native people for bruises, wounds, and asthma. It was used in Europe for gastrointestinal complaints, neuralgia, and whooping cough.

Medicinal Uses:

Herb

  • Other Conditions

Oil

  • PMS, mastalgia, and endometriosis
  • pro-thromotic states, hypertension, intermittent claudication
  • Other Conditions

Prescribing Considerations

The information provided is intended to augment the treatment from a naturopathic doctor or other trained medical professional. Although most herbs are generally safe, it is recommended that you avoid self-prescribing especially when there is an underlying ongoing medical condition, if you are on any prescription medications or if you are pregnant or breastfeeding.

Formulations and Preparation

  • Adult - 2-8g of seed oil daily in divided doses with food
  • Children - 2-6g of seed oil daily in divided doses with food

Best administered with a preservative such as vitamin E, and protected from oxidation

Safety

The safety and prescribing considerations for this herb include:[3], [4]

  • Generally regarded as safe.
  • Side-effects are rare and limited to headache, nausea, and diarrhea. May also cause inhibition of testosterone conversion to dihydrotestosterone.
  • Cautions and Contraindications
  • epilepsy and mania (speculative)
  • Drug-Herb Interactions.[2]
  • Tamoxifen - faster response to the drug in patients with estrogen-dependent breast cancer (human study)
  • Anticoagulants - may be potentiated (speculative)
  • Phenothiazines - when given for schizophrenia, seizures were reported (human study; however, in other case reports patients diagnosed with schizophrenia and treated with phenothiazines were later rediagnosed with having epilepsy)
  • Antiepileptics - may be less effective due to increased risk for seizure (speculative)
  • Colchicine - synergistic in multiple sclerosis for improvement of disability score (human study)
  • NSAIDs - reduced pain from NSAID-induced gastrointestinal lesions (human study)

References

  1. ↑ Boon Heather, Smith Michael (2009) 55 Most Common Medicinal Herbs: The Complete Natural Medicine Guide Second Edition Institute of Naturopathic Education and Research, CCNM Toronto.
  2. ↑ 2.0 2.1 Godfrey Anthony, Saunders Paul, Barlow Kerry, Gowan Matt (2011) Principles and Practices of Naturopathic Botanical Medicine, Advanced Botanical Medicine. V3 CCNM Press, Toronto.
  3. ↑ Stargrove Mitchell Bebell, Treasure Jonathan, McKee Dwight L (2008) Herb, Nutrient and Drug Interactions: Clinical Implications and Therapeutic Strategies.
  4. ↑ Brinker Francis (1997) Herbal Contraindications and Drug Interactions: Plus Herbal Adjuncts With Medicines, 4th Edition Eclectic Medical Publications.